Search Result

Results for "

low affinity

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (7) Adenosine Receptor (3) Adrenergic Receptor (4) Androgen Receptor (1) Apoptosis (3) Bacterial (2) Bcl-2 Family (1) Biochemical Assay Reagents (2) Calcium Channel (1) Caspase (1) CCR (1) Cholinesterase (ChE) (1) Complement System (1) DNA/RNA Synthesis (1) Dopamine Receptor (5) Drug Metabolite (1) Endogenous Metabolite (3) Epigenetic Reader Domain (2) FAP (1) Flavivirus (1) Fluorescent Dye (9) GABA Receptor (2) Glucocorticoid Receptor (2) GPR109A (1) Histamine Receptor (5) Histone Demethylase (1) HPV (1) iGluR (2) Interleukin Related (1) Isotope-Labeled Compounds (3) Lipoxygenase (1) LPL Receptor (1) mAChR (1) Melanocortin Receptor (1) mGluR (2) MicroRNA (2) Mineralocorticoid Receptor (1) Mitochondrial Metabolism (1) nAChR (2) NF-κB (1) NOD-like Receptor (NLR) (1) P-glycoprotein (1) P2X Receptor (1) PPAR (2) PROTACs (3) RAR/RXR (1) Reactive Oxygen Species (1) Renin (2) Ser/Thr Protease (1) Serotonin Transporter (2) SGLT (1) Thyroid Hormone Receptor (1) TNF Receptor (1) Toll-like Receptor (TLR) (1) Trk Receptor (1) VEGFR (1) Virus Protease (2) α-synuclein (1)
By Research Areas:	Cancer (16) Cardiovascular Disease (9) Endocrinology (6) Infection (6) Inflammation/Immunology (10) Metabolic Disease (12) Neurological Disease (26)

By Targets:

5-HT Receptor (7)

Adenosine Receptor (3)

Adrenergic Receptor (4)

Androgen Receptor (1)

Apoptosis (3)

Bacterial (2)

Bcl-2 Family (1)

Biochemical Assay Reagents (2)

Calcium Channel (1)

Caspase (1)

CCR (1)

Cholinesterase (ChE) (1)

Complement System (1)

DNA/RNA Synthesis (1)

Dopamine Receptor (5)

Drug Metabolite (1)

Endogenous Metabolite (3)

Epigenetic Reader Domain (2)

FAP (1)

Flavivirus (1)

Fluorescent Dye (9)

GABA Receptor (2)

Glucocorticoid Receptor (2)

GPR109A (1)

Histamine Receptor (5)

Histone Demethylase (1)

HPV (1)

iGluR (2)

Interleukin Related (1)

Isotope-Labeled Compounds (3)

Lipoxygenase (1)

LPL Receptor (1)

mAChR (1)

Melanocortin Receptor (1)

mGluR (2)

MicroRNA (2)

Mineralocorticoid Receptor (1)

Mitochondrial Metabolism (1)

nAChR (2)

NF-κB (1)

NOD-like Receptor (NLR) (1)

P-glycoprotein (1)

P2X Receptor (1)

PPAR (2)

PROTACs (3)

RAR/RXR (1)

Reactive Oxygen Species (1)

Renin (2)

Ser/Thr Protease (1)

Serotonin Transporter (2)

SGLT (1)

Thyroid Hormone Receptor (1)

TNF Receptor (1)

Toll-like Receptor (TLR) (1)

Trk Receptor (1)

VEGFR (1)

Virus Protease (2)

α-synuclein (1)

By Research Areas:

Cancer (16)

Cardiovascular Disease (9)

Endocrinology (6)

Infection (6)

Inflammation/Immunology (10)

Metabolic Disease (12)

Neurological Disease (26)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Targets Recommended: LDLR LOX-1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-50669

MK-0812

CCR Inflammation/Immunology Endocrinology

MK-0812 is a potent and selective CCR2 antagonist with low nM affinity for CCR2.
HY-110399

Cirsiliol

Lipoxygenase Neurological Disease

Cirsiliol is a potent and selective 5-lipoxygenase inhibitor and a competitive low affinity benzodiazepine receptor ligand.

MK-0812	CCR	Inflammation/Immunology Endocrinology
MK-0812 is a potent and selective CCR2 antagonist with low nM affinity for CCR2.

Cirsiliol	Lipoxygenase	Neurological Disease
Cirsiliol is a potent and selective 5-lipoxygenase inhibitor and a competitive low affinity benzodiazepine receptor ligand.

HY-117959

TAK-615	LPL Receptor	Inflammation/Immunology
TAK-615 is a negative allosteric modulator (NAM) of the LPA1 receptor for the research of pulmonary fibrosis. TAK-615 binds the LPA1 receptor with high affinity (K_d high affinity of 1.7 nM and K_d low affinity of 14.5 nM) .

HY-155471

IMP 245	Others	Others
IMP 245 is a symmetric di-HSG bivalent hapten. IMP 245 has low toxicity, high affinity binding to available antibodies and absence of cross reactivity or non-specific binding with body components .

HY-137103

BTC-AM	Fluorescent Dye	Others
BTC-AM is a low affinity calcium indicator. BTC-AM has substantial calcium-independent fluorescence at all excitation wavelengths. BTC-AM is readily loaded into neurons and is rapidly hydrolysed .

HY-153756

GFP16

Others Infection

GFP16 is a low affinity antiprion compound. GFP16 can be used for research of antiprion drug discovery .

GFP16	Others	Infection
GFP16 is a low affinity antiprion compound. GFP16 can be used for research of antiprion drug discovery .

HY-14953

Imepitoin AWD 131-138	GABA Receptor	Neurological Disease
Imepitoin (AWD 131-138) is a new low-affinity partial benzodiazepine receptor agonist with potent anticonvulsant and anxiolytic properties in rodent models.

HY-137128

BTC tetrapotassium	Fluorescent Dye	Others
BTC tetrapotassium is a low affinity calcium indicator (K_d approximately 7-26 µM) featuring many desirable properties for cellular calcium imaging, including long excitation wavelengths (400/485 nm), low sensitivity to Mg ²⁺, and accuracy of ratiometric measurement .

HY-101356

CPCCOEt

mGluR Neurological Disease

CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of metabotropic glutamate receptor 1b (mGluR1b) .

CPCCOEt	mGluR	Neurological Disease
CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of metabotropic glutamate receptor 1b (mGluR1b) .

HY-10684

Pridopidine ACR16; ASP2314; FR310826	Dopamine Receptor	Neurological Disease
Pridopidine, a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist. Pridopidine exerts high affinity towards sigma 1 receptor (S1R) with K_i between 70 and 80 nM, which is ~100× higher than its affinity toward D2R.

HY-B0371B

(R)-Terazosin	Adrenergic Receptor	Endocrinology
(R)-Terazosin is an active R-enantiomer of Terazosin. (R)-Terazosin is a potent α1-adrenoceptor antagonist with K_i values of 6.51 nM, 1.01 nM and 1.97 nM for α1a, α1b and α1d-adrenoceptor, respectively .

HY-12497

ANA-12 25+ Cited Publications	Trk Receptor	Neurological Disease
ANA-12 is a potent and selective TrkB antagonist with IC₅₀s of 45.6 nM and 41.1 μM for the high and low affinity sites, respectively.

HY-14560A

(R,R)-Reboxetine mesylate (R,R)-FCE20124 mesylate; (R,R)-PNU155950E mesylate	Adrenergic Receptor mAChR	Neurological Disease
(R,R)-Reboxetine mesylate is an antidepressant agent with great bioavailability. (R,R)-Reboxetine is the enantiomer of Reboxetine, which is a selective noradrenaline reuptake inhibitor. Reboxetine consists of (R,R) and (S,S) enantiomer, has low affinity for alpha-adrenergic and muscarinic receptors and low toxicity in animals .

HY-W001909

Myosmine	nAChR	Metabolic Disease
Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a K_i of 3300 nM .

HY-135239

Fura-FF pentapotassium	Fluorescent Dye	Others
Fura-FF pentapotassium is a low-affinity fluorescent dye for calcium (Ex/Em: 365/514 nm in the absence of calcium; 339/507 nm in the presence of a high calcium concentration) .

HY-100799

ZAPA sulfate

ZAPA sulfate is an agonist at low affinity GABA_A-receptors. ZAPA sulfate induces membrane hyperpolarization of the Ascaris muscle cell with an EC₅₀ of 10.3 μM .

ZAPA sulfate
ZAPA sulfate is an agonist at low affinity GABA_A-receptors. ZAPA sulfate induces membrane hyperpolarization of the Ascaris muscle cell with an EC₅₀ of 10.3 μM .

HY-121301

Amperozide	5-HT Receptor	Neurological Disease
Amperozide is an atypical antipsychotic that acts as an antagonist of the 5-HT2 receptor with a K_i value of 26 nM. Amperozide has a low affinity for D2 receptors .

HY-14121

MRS 1754 3 Publications Verification	Adenosine Receptor	Metabolic Disease Inflammation/Immunology
MRS 1754 is a selective antagonist radioligand for A_2B adenosine receptor with very low affinity for A₁ and A₃ receptors of both humans and rats .

HY-107579

Acifran AY 25712	GPR109A	Cardiovascular Disease
Acifran (AY 25712), an antihyperlipidemic agent, is an orally active agonist of GPR109A (HM74A) and GPR109B, the high and low affinity receptors for Niacin .

HY-100703A

Pipamperone dihydrochloride Floropipamide dihydrochloride; McN-JR 3345 dihydrochloride; R 3345 dihydrochloride	Dopamine Receptor 5-HT Receptor	Neurological Disease
Pipamperone (Floropipamide; McN-JR 3345) dihydrochloride is a high-affinity antagonist of 5-HT_2A receptor (pK_i=8.2) and D₄ receptor (pK_i=8.0) and a low-affinity antagonist of D₂ receptor (pK_i=6.7) .

HY-P9973

Brolucizumab DLX1008; ESBA 1008; RTH258	VEGFR	Cancer
Brolucizumab (DLX1008) is a single-chain anti-VEGF-A antibody fragment with low picomolar affinity (K_D=1.05 pM). Brolucizumab can be used for the research of cancer .

HY-100703

Pipamperone Floropipamide; McN-JR 3345; R 3345
Pipamperone (Floropipamide; McN-JR 3345; R 3345) is a high-affinity antagonist of 5-HT_2A receptor (pK_i=8.2) and D₄ receptor (pK_i=8.0) and a low-affinity antagonist of D₂ receptor (pK_i=6.7) .

HY-N11978

6-Hydroxykynurenic acid 6-HKA	iGluR	Neurological Disease
6-Hydroxykynurenic acid (6-HKA) is a derivative of kynurenic acid (KYNA) and can be isolated from Ginkgo leaves. 6-Hydroxykynurenic acid is a low-affinity NMDAR antagonist (IC₅₀: 59 μM) .

HY-153333

A1/A3 AR antagonist 3	Adenosine Receptor	Cardiovascular Disease
A1/A3 AR antagonist 3 is an A₁R/A₃R dual antagonist with high affinity at low-micromolar to low-nanomolar. A1/A3 AR antagonist 3 can be used for the research of chronic heart diseases .

HY-107397

Ch55 2 Publications Verification	RAR/RXR	Cancer
Ch55 is a potent synthetic retinoid. Ch55 binds to RAR-α and RAR-β receptors with high affinity. Ch55 displays low affinity for cellular retinoic acid binding protein (CRABP). Ch55 is a potent inducer of the differentiation of HL60 cells with an EC₅₀ of 200 nM. Ch55 can be used for cancer research .

HY-16688

RU 24969 1 Publications Verification	5-HT Receptor	Neurological Disease
RU 24969 is a preferential 5-HT_1B agonist, with a K_i of 0.38 nM, but also displays appreciable affinity for the 5-HT_1A receptor (K_i=2.5 nM), and has low affinity for other receptor sites in the brain. RU 24969 could decrease fluid consumption and increase forward locomotion .

HY-D0157

ZnAF-2 ZnAF2; ZnAF 2; 4-[(2-{Bis[(pyridin-2-YL)methyl]amino}ethyl)amino]-2-(6-hydroxy-3-oxo-3H-xanthen-9-YL)benzoic acid	Biochemical Assay Reagents	Others
ZnAF-2, 6-iso- is a cell-impermeable compound that acts as a high-affinity Zn2 -specific fluorescent probe (Kd = 2.7 nM). It exhibits low basal fluorescence with an approximately 51-fold increase in fluorescence intensity upon stoichiometric (1:1) binding to Zn2 . Little affinity for Ca2 , Mg2 , Na or K .

HY-163079

AlF-PD-FAPI	FAP	Cancer
AlF-PD-FAPI has affinity for FAP , with the IC₅₀ of 0.13 nM, and shows a specific uptake, high internalized fraction, and low cellular efflux in vitro. AlF-PD-FAPI can be used as FAP-targeting tracer .

HY-122025

AC-262536 1 Publications Verification	Androgen Receptor	Metabolic Disease
AC-262536 is a selective and non-steroidal androgen receptor modulators (SARMs) with beneficial anabolic effects. AC-262536 exhibits potent agonist activity at the androgen receptor, with an affinity in the low nanomolar range (1-10 nM) .

HY-16688B

RU 24969 hemisuccinate	5-HT Receptor	Neurological Disease
RU 24969 hemisuccinate is a preferential 5-HT_1B agonist, with a K_i of 0.38 nM, but also displays appreciable affinity for the 5-HT_1A receptor (K_i=2.5 nM), and has low affinity for other receptor sites in the brain. RU 24969 hemisuccinate could decrease fluid consumption and increase forward locomotion .

HY-W001909S

Myosmine-d4	nAChR	Metabolic Disease
Myosmine-d₄ is the deuterium labeled Myosmine. Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM[1][2].

HY-15553B

Mibefradil dihydrochloride hydrate Ro 40-5967 dihydrochloride hydrate	Calcium Channel	Cardiovascular Disease
Mibefradil dihydrochloride hydrate (Ro 40-5967 dihydrochloride hydrate) is a effectively long-acting calcium channel antagonist, used as an antihypertensive agent. Mibefradil dihydrochloride hydrate acts via a higher affinity block for low-voltage-activated (T) than for high-voltage-activated (L) calcium channels .

HY-15234

Fluticasone furoate	Glucocorticoid Receptor	Inflammation/Immunology
Fluticasone furoate is a topical, intranasal, enhanced-affinity synthetic trifluorinated corticosteroid with a K_d of 0.3 nM. Fluticasone furoate has potent anti-inflamatory and anti-asthmatic activity, and low systemic exposure. Fluticasone furoate has the potential for allergic rhinitis treatment .

HY-136587

Oxomemazine	Histamine Receptor mGluR	Inflammation/Immunology
Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic properties. Oxomemazine is a selective antagonist for muscarinic M1 receptor, displays about 20-fold difference in the affinity for high (K_i= 84 nM, M1 receptor) and low (K_i= 1.65 μM, M2 receptor) affinity sites . Oxomemazine an antihistamine and anticholinergic agent used for the study of cough treatment .

HY-10915

LUF6096	Adenosine Receptor	Cardiovascular Disease
LUF6096, a potent allosteric enhancer of the adenosine A3 receptor, is able to allosterically enhance agonist binding. LUF6096 shows low orthosteric affinity for any of the adenosine receptors. LUF6096 shows protective effects in myocardial ischemia/reperfusion injury .

HY-D1447

Fluo-3FF pentapotassium	Fluorescent Dye	Others
Fluo-3FF pentapotassium is a cell-permeable acetoxy-methyl ester of Fluo-3FF, a fluorescent calcium indicator. Fluo-3FF is a di-fluorinated analog of Fluo-3 with a 100-fold lower affinity than Fluo-3 for calcium (Kds = 42 and 0.4 碌M, respectively). For its low affinity, Fluo-3FF is used for studying compartments with high concentrations of calcium, such as endoplasmic reticulum, where high affinity dyes will be insensitive to luminal fluctuations.

HY-101232

Tiotidine ICI 125211
Tiotidine (ICI 125211) is a potent and selective antagonist of histamine H2-receptor (pA₂=7.3-7.8 for guinea-pig right atrium). Tiotidine has low affinity for both the H1 and the H3 receptors .

HY-107031

Metapramine 19560 RP	iGluR	Others
Metapramine (19560 RP) is an antidepressant agent, belonging to the class of tricyclic compounds . Metapramine inhibits norepinephrine reuptake, without affecting the reuptake of serotonin or dopamine . Metapramine is a low-affinity antagonist of the N-methyl-D-aspartic acid (NMDA) receptor complex channel .

HY-119993

AR03 BMH-23	DNA/RNA Synthesis	Cancer
AR03 (BMH-23) is an apurinic/apyrimidinic endonuclease 1 (Ape1) inhibitor with an IC₅₀ of 2.1 µM. AR03 has low affinity for double-stranded DNA. AR03 potentiates the cytotoxicity of methyl methanesulfonate and temozolomide in SF767 cells .

HY-14567

Ciproxifan FUB-359	Histamine Receptor	Neurological Disease Endocrinology
Ciproxifan (FUB 359) is a potent, selective, orally bioavailable and competitive antagonist of histamine H₃-receptor, with an IC₅₀ of 9.2 nM. Ciproxifan displays low apparent affinity at other receptor subtypes. Ciproxifan can be used for the research of aging disorders and Alzheimer's disease .

HY-15289

Ciproxifan maleate FUB 359 maleate	Histamine Receptor	Neurological Disease Endocrinology
Ciproxifan maleate (FUB 359 maleate) is a potent, selective, orally bioavailable and competitive antagonist of histamine H₃-receptor, with an IC₅₀ of 9.2 nM. Ciproxifan maleate displays low apparent affinity at other receptor subtypes. Ciproxifan maleate can be used for the research of aging disorders and Alzheimer's disease .

HY-108673

Ro 0437626	P2X Receptor	Cancer
Ro 0437626 is a selective purinergic (P2X₁) receptor antagonist (IC₅₀ = 3 μM), but shows low affinity for P2X2, P2X3 and P2X2/3 receptors (IC₅₀ > 100 μM) .

HY-108022

Azemiglitazone MSDC-0602	Mitochondrial Metabolism PPAR	Neurological Disease Metabolic Disease Inflammation/Immunology
Azemiglitazone (MSDC-0602) is an orally active thiazolidinedione (TZD) -like molecule, which binds to PPARγ with low binding and activating affinity. Azemiglitazone inhibits mitochondrial pyruvate carrier (MPC), which inhibits Alzheimer’s disease and diminishes nonalcoholic steatohepatitis (NASH) caused liver injury .

HY-10473

Eprotirome KB2115	Thyroid Hormone Receptor	Metabolic Disease Endocrinology
Eprotirome (KB2115) is a liver-selective thyroid hormone receptor (TR) agonist. KB2115 has modestly higher affinity for TRβ than for TRα. Eprotirome reduces low-density lipoprotein (LDL) cholesterol concentrations. Eprotirome can be used for dyslipidemias and obesity research .

HY-130245

PCSK9 degrader 1	Ser/Thr Protease	Metabolic Disease
PCSK9 degrader 1 (Compound 16) is a small molecule ligand for proprotein convertase substilisin-like/kexin type 9 (PCSK9) and shows high affinity to PCSK9 with a K_i of 107 nM. PCSK9 degrader 1 can involve in a protein-protein interaction with the low-density lipoprotein (LDL) receptor .

HY-B0251S

Eplerenone-d3 Epoxymexrenone-d₃	Mineralocorticoid Receptor Endogenous Metabolite	Cardiovascular Disease
Eplerenone-d₃ is the deuterium labeled Eplerenone. Eplerenone (Epoxymexrenone) is a selective, competitive and oreally active aldosterone antagonist with an IC50 of 138 nM. Eplerenone has low affinity for progesterone, androgen, estrogen and glucocorticoid receptors. Eplerenone can be used for hypertension and heart failure after myocardial infarction reserch[1][2].

HY-119696S

MTIC-d3	Isotope-Labeled Compounds Drug Metabolite	Neurological Disease Cancer
MTIC-d₃ is deuterium labeled MTIC. MTIC is the active metabolite of Temozolomide (TMZ). MITC has lower bioavailability in the brain compared with TMZ, because the agent’s permeability through biological barriers and tumor cell membranes affects bioavailability. MITC exhibits low affinity to biological membrane[1].

HY-122653

CCT367766	PROTACs	Cancer
CCT367766 is a potent and the third generation heterobifunctional and Cereblon-based pirin targeting protein degradation probe (PDP, or PROTAC), depletes pirin protein expression at low concentration. CCT367766 exhibits a moderate affinity for the CRBN-DDB1 complex with an IC₅₀ value of 490 nM. CCT367766 reveals a good affinity for the recombinant pirin and CRBN with K_d values of 55 nM and 120 nM, respectively. CCT367766 provides a potential chemical tool to study a largely unexplored protein .

HY-106100A

Roxindole hydrochloride EMD 38362	Dopamine Receptor Serotonin Transporter	Neurological Disease
Roxindole hydrochloride (EMD 38362), an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors, with an affinity for the D2-like subtype in the low nanomolar range. Roxindole can be used for the research of positive and negative schizophrenic symptoms. Roxindole is a 5-HT_1A agonist and 5-HT uptake inhibitor with high affinity for 5-HT_1A (IC₅₀=0.9 nM). Antipsychotic and antidepressant activities .

HY-122653A

CCT367766 formic	PROTACs	Cancer
CCT367766 formic is a potent and the third generation heterobifunctional and Cereblon-based pirin targeting protein degradation probe (PDP, or PROTAC), depletes pirin protein expression at low concentration. CCT367766 formic exhibits a moderate affinity for the CRBN-DDB1 complex with an IC₅₀ value of 490 nM. CCT367766 formic reveals a good affinity for the recombinant pirin and CRBN with K_d values of 55 nM and 120 nM, respectively. CCT367766 formic provides a potential chemical tool to study a largely unexplored protein .

Cat. No.	Product Name	Type

HY-D0716

Fluo-3AM 5 Publications Verification Fluo-3-pentaacetoxymethyl ester	Fluorescent Dyes/Probes
Fluo-3 AM is a fluorecent Ca ²⁺ chelator, with high affinity for calcium. Fluo-3 AM can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence .

HY-130575

Fura-FF AM	Fluorescent Dyes/Probes
Fura-FF AM is a cell-permeable acetoxymethyl ester of fura-FF, a dluorescent calcium indicator. Fura-FF AM is hydrolyzed by intracellular esterases to release fura-FF in cells. Fura-FF is a difluorinated derivative of the calcium indicator fura-2. Compared to fura-2, fura-FF has a low affinity for calcium and is suitable for studying compartments with high concentrations of calcium.

HY-137103

BTC-AM	Fluorescent Dyes/Probes
BTC-AM is a low affinity calcium indicator. BTC-AM has substantial calcium-independent fluorescence at all excitation wavelengths. BTC-AM is readily loaded into neurons and is rapidly hydrolysed .

HY-135239

Fura-FF pentapotassium	Fluorescent Dyes/Probes
Fura-FF pentapotassium is a low-affinity fluorescent dye for calcium (Ex/Em: 365/514 nm in the absence of calcium; 339/507 nm in the presence of a high calcium concentration) .

HY-D1447

Fluo-3FF pentapotassium

Fluorescent Dyes/Probes

Fluo-3FF pentapotassium is a cell-permeable acetoxy-methyl ester of Fluo-3FF, a fluorescent calcium indicator. Fluo-3FF is a di-fluorinated analog of Fluo-3 with a 100-fold lower affinity than Fluo-3 for calcium (Kds = 42 and 0.4 碌M, respectively). For its low affinity, Fluo-3FF is used for studying compartments with high concentrations of calcium, such as endoplasmic reticulum, where high affinity dyes will be insensitive to luminal fluctuations.

HY-101902

Quin-2AM Quin-2 acetoxymethyl ester	Fluorescent Dyes/Probes
Quin-2AM is a fluorecent Ca ²⁺ chelator, with high affinity for calcium. Quin-2AM can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence .

HY-D1498

Mag-Fluo-4 AM 1 Publications Verification	Fluorescent Dyes/Probes
Mag-Fluo-4 AM is a fluorecent Ca ²⁺ chelator, with high affinity for calcium. Mag-Fluo-4 AM can specifically identify intracellular calcium ions, with high sensitivity, low cytotoxicity, increased AM acetylmethyl ester can enter the cell well, after being sheared by the intracellular esterase stay in the cell to bind to calcium ions, produce strong fluorescence .

HY-D1755

Fluo-3FF AM	Fluorescent Dyes/Probes
Fluo-3FF AM is a low affinity (Kd = 42 μM) fluorescent Ca ²⁺ sensitive indicator (Abs/Em = 462 nm/526 nm). Fluo-3FF AM is Mg ²⁺ insensitive and relatively photostable. Fluo-3FF AM is an analog of Fluo-3FF AM. Fluo-3FF AM is essentially non-fluorescent, but exhibits a strong fluorescence enhancement upon entry into cells and binding to calcium.

Cat. No.	Product Name	Type

HY-126726

KOdiA-PC

Biochemical Assay Reagents

Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species that are cytotoxic and proatherogenic. Many of these species were recently isolated and purified from oxLDL and identified as phosphatidylcholine species containing fragmented oxidized short-chain fatty acid residues at the sn-2 position. 1-(Palmitoyl)-2-(5-keto-6-octene-dioyl)phosphatidylcholine or KOdiA-PC is one of the most potent CD36 ligands of the oxLDL species. KOdiA-PC confers CD36 scavenger receptor binding affinity to LDL at a frequency of only 2 to 3 KOdiA-PC molecules/LDL particle and may be one of the more important structural determinants of oxLDL.

HY-Y0320

Dimethyl sulfoxide

85+ Cited Publications

DMSO

Co-solvents

Dimethyl sulfoxide (DMSO) is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties .
MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition).

HY-D0157

ZnAF-2 ZnAF2; ZnAF 2; 4-[(2-{Bis[(pyridin-2-YL)methyl]amino}ethyl)amino]-2-(6-hydroxy-3-oxo-3H-xanthen-9-YL)benzoic acid	Biochemical Assay Reagents
ZnAF-2, 6-iso- is a cell-impermeable compound that acts as a high-affinity Zn2 -specific fluorescent probe (Kd = 2.7 nM). It exhibits low basal fluorescence with an approximately 51-fold increase in fluorescence intensity upon stoichiometric (1:1) binding to Zn2 . Little affinity for Ca2 , Mg2 , Na or K .

Cat. No.	Product Name	Target	Research Area

HY-P3912A

Endotoxin inhibitor TFA	Peptides	Infection
Endotoxin inhibitor TFA is a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS (HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor TFA inhibits the febrile response to LPS with very low toxicity and lethality .

HY-106178

PMX-53 3 Publications Verification 3D53	Complement System	Cardiovascular Disease Inflammation/Immunology Cancer
PMX-53 (3D53) is a synthetic peptidic and a potent and orally active complement C5a receptor (CD88) antagonist with an IC₅₀ of 20 nM. PMX-53 is also a low-affinity MrgX2 agonist that stimulates MrgX2-mediated mast cell degranulation. PMX-53 specifically binds to C5aR1 and does not bind to the second C5aR (C5L2) and C3aR. PMX-53 has anti-inflammatory, anticancer and antiatherosclerotic effects .

HY-P5085

Acetyl-Octreotide	Peptides	Others
Acetyl-octreotide is a reduced linear peptide. Acetyl-octreotide can synthesize Re(V)-cyclized peptides in aqueous methanol solutions with **low Sst receptor binding affinities** .

HY-P3912

Endotoxin inhibitor	Peptides	Infection
Endotoxin inhibitor a synthetic peptide that binds lipid A with high affinity, thereby detoxifying LPS (HY-D1056) and preventing LPS-induced cytokine release in vivo. Endotoxin inhibitor inhibits the febrile response to LPS with very low toxicity and lethality .

HY-P5396

GAD65 (524-543)	Peptides	Others
GAD65 (524-543) is a biological active peptide. (This is amino acids 524 to 543 fragment of glutamic acid decarboxylase 65 (GAD65). It is one of the first fragments of this islet antigen to induce proliferative T cell responses in the non-obese diabetic (NOD) mouse model of spontaneous autoimmune diabetes. This peptide is a specific, possibly low affinity, stimulus for the spontaneously arising diabetogenic T cell clone BDC2.5. Immunization with p524–543 increases the susceptibility of the NOD mice to type 1 diabetes induced by the adoptive transfer of BDC2.5 T cells.)

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-110399

Cirsiliol	Structural Classification Flavonoids Flavones Leguminosae Source classification Phenols Polyphenols Abrus precatorius Linn. Plants	Lipoxygenase
Cirsiliol is a potent and selective 5-lipoxygenase inhibitor and a competitive low affinity benzodiazepine receptor ligand.

HY-W001909

Myosmine	Alkaloids Pyrrole Alkaloids Classification of Application Fields Nicotiana tabacum L. Source classification Pyridine Alkaloids Metabolic Disease Plants Solanaceae Disease Research Fields	nAChR
Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a K_i of 3300 nM .

HY-Y0320

Dimethyl sulfoxide 85+ Cited Publications DMSO	Microorganisms Source classification	Bacterial Cholinesterase (ChE)
Dimethyl sulfoxide (DMSO) is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties . MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition).

HY-N11978

6-Hydroxykynurenic acid 6-HKA	Structural Classification Ginkgoaceae Ketones, Aldehydes, Acids Source classification Plants Ginkgo biloba	iGluR
6-Hydroxykynurenic acid (6-HKA) is a derivative of kynurenic acid (KYNA) and can be isolated from Ginkgo leaves. 6-Hydroxykynurenic acid is a low-affinity NMDAR antagonist (IC₅₀: 59 μM) .

HY-14520A

(6S)-Tetrahydrofolic acid (6S)-5,6,7,8-Tetrahydrofolic acid; (6S)-Tetrahydrofolic acid	Human Gut Microbiota Metabolites Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
(6S)-Tetrahydrofolic acid is 1000-fold more active than the (6R) form at promoting the binding of fluorodeoxyuridylate to thymidylate synthase and 600-fold more active as a growth factor of P. cerevisiae. (6S)-Tetrahydrofolic acid also has a low affinity and high dissociation rate for folate-binding protein .

Species:	Human (19) Rhesus Macaque (4) Rat (4) Mouse (9) Cynomolgus (5)
Tag:	His (36) SUMO (1) Tag Free (2) Avi (13) Myc (1) Fc (2)
Source:	HEK293 (35) E. coli Cell-free (1) CHO (3) E. coli (2)

Cat. No.	Compare	Product Name	Species	Source

HY-P77314

	Fc gamma RIII/CD16 Protein, Rhesus Macaque (His) low affinity immunoglobulin gamma Fc region receptor III; FcRIII; FCGR3	Rhesus Macaque	HEK293
	The Fc gamma RIII/CD16 protein is a receptor for IgG and is optimally activated upon binding to aggregated antigen-IgG complexes, initiating antibody-dependent cellular cytotoxicity (ADCC) and preventing inappropriate effector cell activation. It mediates IgG effector functions on NK cells, generating memory-like adaptive NK cells to efficiently eliminate virally infected cells. Fc gamma RIII/CD16 Protein, Rhesus Macaque (His) is the recombinant Rhesus Macaque-derived Fc gamma RIII/CD16 protein, expressed by HEK293 , with C-His labeled tag. The total length of Fc gamma RIII/CD16 Protein, Rhesus Macaque (His) is 190 a.a., with molecular weight of ~32-41 KDa.

HY-P74320

	CD23/Fc epsilon RII Protein, Rat (HEK293, Fc) low affinity immunoglobulin epsilon Fc receptor; BLAST-2; FCER2; CD23A	Rat	HEK293
	CD23, also known as Fc epsilon Receptor II (Fc epsilon RII), is a low-affinity receptor for immunoglobulin E (IgE) and complement receptor 2 (CR2/CD21). CD23 regulates IgE production and B-cell differentiation, aiding in IGE-dependent antigen uptake. CD23/Fc epsilon RII Protein, Rat (HEK293, Fc) is the recombinant rat-derived CD23/Fc epsilon RII protein, expressed by HEK293 , with N-hFc labeled tag. The total length of CD23/Fc epsilon RII Protein, Rat (HEK293, Fc) is 282 a.a., with molecular weight of 60-75 kDa.

HY-P77312

	Fc gamma RIII/CD16 Protein, Rhesus Macaque (His-Avi) low affinity immunoglobulin gamma Fc region receptor III; FcRIII; FCGR3	Rhesus Macaque	HEK293
	The Fc gamma RIII/CD16 protein is a receptor for IgG and is optimally activated upon binding to aggregated antigen-IgG complexes, initiating antibody-dependent cellular cytotoxicity (ADCC) and preventing inappropriate effector cell activation. It mediates IgG effector functions on NK cells, generating memory-like adaptive NK cells to efficiently eliminate virally infected cells. Fc gamma RIII/CD16 Protein, Rhesus Macaque (His-Avi) is the recombinant Rhesus Macaque-derived Fc gamma RIII/CD16 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Fc gamma RIII/CD16 Protein, Rhesus Macaque (His-Avi) is 208 a.a., with molecular weight of ~25.3 KDa.

HY-P74321

	CD23/Fc epsilon RII Protein, Mouse (HEK293, His) low affinity immunoglobulin epsilon Fc receptor; BLAST-2; FCER2; CD23A	Mouse	HEK293
	CD23/Fc epsilon RII Protein, a low-affinity receptor for IgE and CR2/CD21, regulates IgE production and B cell differentiation. On B cells, it initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, IgE binding induces intracellular killing of parasites through the L-Arginine-nitric oxide pathway. CD23/Fc epsilon RII homotrimer interacts with IGHE to regulate IgE homeostasis and with CR2/CD21 for binding. CD23/Fc epsilon RII Protein, Mouse (HEK293, His) is the recombinant mouse-derived CD23/Fc epsilon RII protein, expressed by HEK293 , with N-His labeled tag. The total length of CD23/Fc epsilon RII Protein, Mouse (HEK293, His) is 282 a.a., with molecular weight of 33-43 kDa.

HY-P75206

	Fc gamma RIIIB/CD16b Protein, Human low affinity immunoglobulin gamma Fc region receptor III-B; FcR-10; FCG3; FCGR3	Human	E. coli
	Fc gamma RIIIB/CD16b Protein, a low-affinity receptor for IgG, binds complexed or monomeric IgG. Unlike Fc gamma RIIIA, it cannot mediate antibody-dependent cytotoxicity or phagocytosis. Instead, Fc gamma RIIIB may act as a trap for immune complexes, circulating without activating neutrophils. Existing as a monomer, it interacts with INPP5D/SHIP1, implying its role in intracellular signaling pathways linked to immune responses. Fc gamma RIIIB/CD16b Protein, Human is the recombinant human-derived Fc gamma RIIIB/CD16b protein, expressed by E. coli , with tag free. The total length of Fc gamma RIIIB/CD16b Protein, Human is 176 a.a., with molecular weight of ~22 kDa.

HY-P75204

	Fc gamma RIIIB/CD16b Protein, Human (Biotinylated) low affinity immunoglobulin gamma Fc region receptor III-B; FcR-10; FCG3; FCGR3	Human	E. coli
	Fc gamma RIIIB/CD16b Protein, a low-affinity receptor for IgG, binds complexed or monomeric IgG. Unlike Fc gamma RIIIA, it cannot mediate antibody-dependent cytotoxicity or phagocytosis. Instead, Fc gamma RIIIB may act as a trap for immune complexes, circulating without activating neutrophils. Existing as a monomer, it interacts with INPP5D/SHIP1, implying its role in intracellular signaling pathways linked to immune responses. Fc gamma RIIIB/CD16b Protein, Human (Biotinylated) is the recombinant human-derived Fc gamma RIIIB/CD16b protein, expressed by E. coli , with tag free. The total length of Fc gamma RIIIB/CD16b Protein, Human (Biotinylated) is 176 a.a., with molecular weight of ~20 kDa.

HY-P76918

	FcgR4/CD16-2 Protein, Mouse (HEK293, His) low affinity immunoglobulin gamma Fc region receptor IV; CD16-2; FcgammaRIV; Fcrl3	Mouse	HEK293
	The FcγR4/CD16-2 protein is an IgG receptor with moderate affinity for IgG2a and IgG2b. It recognizes virus-specific IgG, triggers antibody-dependent cellular cytotoxicity, and provides protection against fatal influenza infection. FcgR4/CD16-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived FcgR4/CD16-2 protein, expressed by HEK293 , with C-His labeled tag. The total length of FcgR4/CD16-2 Protein, Mouse (HEK293, His) is 185 a.a., with molecular weight of 25-35 kDa.

HY-P77313

	Fc gamma RIII/CD16 Protein, Rhesus Macaque (Biotinylated, HEK293, His-Avi) low affinity immunoglobulin gamma Fc region receptor III; FcRIII; FCGR3	Rhesus Macaque	HEK293
	The Fc gamma RIII/CD16 protein is a receptor for IgG and is optimally activated upon binding to aggregated antigen-IgG complexes, initiating antibody-dependent cellular cytotoxicity (ADCC) and preventing inappropriate effector cell activation. It mediates IgG effector functions on NK cells, generating memory-like adaptive NK cells to efficiently eliminate virally infected cells. Fc gamma RIII/CD16 Protein, Rhesus Macaque (Biotinylated, HEK293, His-Avi) is the recombinant Rhesus Macaque-derived Fc gamma RIII/CD16 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Fc gamma RIII/CD16 Protein, Rhesus Macaque (Biotinylated, HEK293, His-Avi) is 208 a.a., with molecular weight of ~25.3 KDa.

HY-P76916

	FcgR4/CD16-2 Protein, Mouse (HEK293, His-Avi) low affinity immunoglobulin gamma Fc region receptor IV; CD16-2; FcgammaRIV; Fcrl3	Mouse	HEK293
	The FcγR4/CD16-2 protein is an IgG receptor with moderate affinity for IgG2a and IgG2b. It recognizes virus-specific IgG, triggers antibody-dependent cellular cytotoxicity, and provides protection against fatal influenza infection. FcgR4/CD16-2 Protein, Mouse (HEK293, His-Avi) is the recombinant mouse-derived FcgR4/CD16-2 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of FcgR4/CD16-2 Protein, Mouse (HEK293, His-Avi) is 185 a.a., with molecular weight of 25-35 kDa.

HY-P76917

	FcgR4/CD16-2 Protein, Mouse (Biotinylated, HEK293, His-Avi) low affinity immunoglobulin gamma Fc region receptor IV; CD16-2; FcgammaRIV; Fcrl3	Mouse	HEK293
	The FcγR4/CD16-2 protein is an IgG receptor with moderate affinity for IgG2a and IgG2b. It recognizes virus-specific IgG, triggers antibody-dependent cellular cytotoxicity, and provides protection against fatal influenza infection. FcgR4/CD16-2 Protein, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived FcgR4/CD16-2 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of FcgR4/CD16-2 Protein, Mouse (Biotinylated, HEK293, His-Avi) is 185 a.a., with molecular weight of 35-40 kDa.

HY-P75202

	Fc gamma RIIIB/CD16b Protein, Human (NA2, CHO, His) low affinity immunoglobulin gamma Fc region receptor III-B; FcR-10; FCG3; FCGR3	Human	CHO
	Fc gamma RIIIB/CD16b Protein, a low-affinity receptor for IgG, binds complexed or monomeric IgG. Unlike Fc gamma RIIIA, it cannot mediate antibody-dependent cytotoxicity or phagocytosis. Instead, Fc gamma RIIIB may act as a trap for immune complexes, circulating without activating neutrophils. Existing as a monomer, it interacts with INPP5D/SHIP1, implying its role in intracellular signaling pathways linked to immune responses. Fc gamma RIIIB/CD16b Protein, Human (NA2, CHO, His) is the recombinant human-derived Fc gamma RIIIB/CD16b protein, expressed by CHO , with C-His labeled tag. The total length of Fc gamma RIIIB/CD16b Protein, Human (NA2, CHO, His) is 184 a.a., with molecular weight of 38-43 kDa.

HY-P72748

	CD23/Fc epsilon RII Protein, Human (HEK293, His) low affinity immunoglobulin epsilon Fc receptor; BLAST-2; FCER2; CD23A; CLEC4J; FCE2; IGEBF	Human	HEK293
	CD23 or Fc epsilon receptor II (Fc epsilon RII) is a low-affinity receptor for immunoglobulin E (IgE) and complements receptor 2 (CR2/CD21). CD23 is present on B cells, regulates IgE production and B cell differentiation, and aids in IgE-dependent antigen uptake. CD23/Fc epsilon RII Protein, Human (HEK293, His) is the recombinant human-derived CD23/Fc epsilon RII protein, expressed by HEK293 , with N-8*His labeled tag. The total length of CD23/Fc epsilon RII Protein, Human (HEK293, His) is 274 a.a., with molecular weight of 35-40 kDa.

HY-P75207

	Fc gamma RIIIA/CD16a Protein, Human (CHO, His) low affinity immunoglobulin gamma Fc region receptor III-A; FcRIIIa; FcR-10; CD16a; FCGR3A; IGFR3	Human	CHO
	Fc gamma RIIIA/CD16a protein is a receptor for the Fc fragment of IgG and activates antibody-dependent cellular cytotoxicity (ADCC) upon binding to antigen-IgG complexes. It mediates IgG effector functions on NK cells, generating memory-like adaptive NK cells to efficiently eliminate virally infected cells. Fc gamma RIIIA/CD16a Protein, Human (CHO, His) is the recombinant human-derived Fc gamma RIIIA/CD16a protein, expressed by CHO , with C-His labeled tag. The total length of Fc gamma RIIIA/CD16a Protein, Human (CHO, His) is 192 a.a., with molecular weight of ~23.3 kDa.

HY-P75647

	Fc gamma RIIA/CD32a Protein, Rhesus Macaque (HEK293, His) low affinity Immunoglobulin Gamma Fc Region Receptor II-a; CD32; FCGR2A; FCG2; IGFR2	Rhesus Macaque	HEK293
	The Fc γ RIIA/CD32a protein plays a key role by specifically binding to the Fc region of immunoglobulin γ, acting as a low-affinity receptor. Fc γ RIIA/CD32a initiates cellular responses against pathogens and soluble antigens and plays an important role in immune regulation. Fc γ RIIA/CD32a interacts with PI3K and Syk. Fc gamma RIIA/CD32a Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived Fc gamma RIIA/CD32a protein, expressed by HEK293 , with C-His labeled tag. The total length of Fc gamma RIIA/CD32a Protein, Rhesus Macaque (HEK293, His) is 184 a.a., with molecular weight of ~25-35 kDa.

HY-P72735

	Fc gamma RIIB/CD32b Protein, Mouse (181a.a, HEK293, His) low affinity immunoglobulin gamma Fc region receptor II; Fc-gamma-RIIB; Ly-17; CD32; Fcgr2	Mouse	HEK293
	Fc gamma RIIB/CD32b protein is a low-affinity receptor for immunoglobulin gamma and is involved in a variety of effector and regulatory functions. When co-aggregated with BCR, TCR and Fc receptors, it promotes endocytosis of soluble immune complexes (IIB2), modulates antibody production, and downregulates B-cell, T-cell and mast cell activation. Fc gamma RIIB/CD32b Protein, Mouse (181a.a, HEK293, His) is the recombinant mouse-derived Fc gamma RIIB/CD32b protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Fc gamma RIIB/CD32b Protein, Mouse (181a.a, HEK293, His) is 181 a.a., with molecular weight of ~33 kDa.

HY-P75621

	Fc gamma RIIIA/CD16a Protein, Rat (HEK293, His) low affinity immunoglobulin gamma Fc region receptor III-A; FcRIIIa; FcR-10; CD16a; FCGR3A; IGFR3	Rat	HEK293
	Fc γ RIIIA/CD16a is a receptor for the invariant Fc fragment of immunoglobulin γ (IgG). Fc γ RIIIA/CD16a regulates NK cell survival and proliferation and prevents NK cell progenitor cell apoptosis. Fc γ RIIIA/CD16a plays a role in mediating the anti-tumor activity of therapeutic antibodies by triggering TNFA-dependent ADCC, which promotes the entry of the virus into bone marrow cells during secondary infection and subsequent viral replication through antibody-dependent enhancement (ADE). Fc gamma RIIIA/CD16a Protein, Rat (HEK293, His) is the recombinant rat-derived Fc gamma RIIIA/CD16a protein, expressed by HEK293 , with C-His labeled tag. The total length of Fc gamma RIIIA/CD16a Protein, Rat (HEK293, His) is 179 a.a., with molecular weight of 28-33 kDa.

HY-P75642

Fc gamma RIIA/CD32a Protein, Cynomolgus (Biotinylated, HEK293, His-Avi)

low affinity Immunoglobulin Gamma Fc Region Receptor II-a; CD32; FCGR2A; FCG2; IGFR2
Cynomolgus HEK293

HY-P75644

	Fc gamma RIIA/CD32a Protein, Human (H167R, HEK293, Fc) low affinity Immunoglobulin Gamma Fc Region Receptor II-a; CD32; FCGR2A; FCG2; IGFR2	Human	HEK293
	Fc gamma RIIA/CD32a Protein plays a pivotal role, specifically binding to the Fc region of immunoglobulins gamma as a low-affinity receptor. Interacting with IgG, it initiates cellular responses against pathogens, crucial for immune modulation. Notably, the protein promotes opsonized antigen phagocytosis, contributing to immune defense. Engaging with IGHG1, INPP5D/SHIP1, INPPL1/SHIP2, APCS, FGR, and HCK, it participates in intricate signaling pathways, highlighting its multifaceted role in orchestrating diverse immune responses. Fc gamma RIIA/CD32a Protein, Human (H167R, HEK293, Fc) is the recombinant human-derived Fc gamma RIIA/CD32a protein, expressed by HEK293 , with C-hFc labeled tag and H167R mutation. The total length of Fc gamma RIIA/CD32a Protein, Human (H167R, HEK293, Fc) is 185 a.a., with molecular weight of ~55 kDa.

HY-P700642

	Fc gamma RIIA/CD32a Protein, Human (185a.a, HEK293, His) low affinity Immunoglobulin Gamma Fc Region Receptor II-a; CD32; FCGR2A; FCG2; IGFR2	Human	HEK293
	Fc gamma RIIA/CD32a Protein plays a pivotal role, specifically binding to the Fc region of immunoglobulins gamma as a low-affinity receptor. Interacting with IgG, it initiates cellular responses against pathogens, crucial for immune modulation. Notably, the protein promotes opsonized antigen phagocytosis, contributing to immune defense. Engaging with IGHG1, INPP5D/SHIP1, INPPL1/SHIP2, APCS, FGR, and HCK, it participates in intricate signaling pathways, highlighting its multifaceted role in orchestrating diverse immune responses. Fc gamma RIIA/CD32a Protein, Human (185a.a, HEK293, His) is the recombinant human-derived Fc gamma RIIA/CD32a protein, expressed by HEK293 , with C-6*His labeled tag and H167 mutation. The total length of Fc gamma RIIA/CD32a Protein, Human (185a.a, HEK293, His) is 185 a.a., with molecular weight of 28-34 KDa.

HY-P702443

	SLC5A2 Protein, Human (Cell-Free, His, SUMO, Myc) Sodium/glucose cotransporter 2; low affinity sodium-glucose cotransporter; Solute carrier family 5 member 2	Human	E. coli Cell-free
	The SLC5A2 protein, as an electrogenic Na(+)-coupled sugar symporter, actively promotes D-glucose transport across the plasma membrane with a precise Na(+) to sugar coupling ratio of 1:1. As observed in various studies, transporter activity is powered by the transmembrane Na(+) electrochemical gradient established by the Na(+)/K(+) pump. SLC5A2 Protein, Human (Cell-Free, His, SUMO, Myc) is the recombinant human-derived SLC5A2 protein, expressed by E. coli Cell-free , with N-10*His, C-Myc, N-SUMO labeled tag. The total length of SLC5A2 Protein, Human (Cell-Free, His, SUMO, Myc) is 102 a.a., with molecular weight of 30.5 kDa.

HY-P75621A

Fc gamma RIIIA/CD16a Protein, Rat (HEK293, C-His)

low affinity immunoglobulin gamma Fc region receptor III-A; FcRIIIa; FcR-10; CD16a; FCGR3A; IGFR3
Rat HEK293

HY-P75210

	Fc gamma RIIIA/CD16a Protein, Human (F176V, CHO, His) low affinity immunoglobulin gamma Fc region receptor III-A; FcRIIIa; FcR-10; CD16a; FCGR3A; IGFR3	Human	CHO
	Fc gamma RIIIA/CD16a Protein, a receptor for the Fc fragment of IgG, activates antibody-dependent cellular cytotoxicity (ADCC) upon binding antigen-IgG complexes. It mediates IgG effector functions on NK cells, generating memory-like adaptive NK cells for efficient virus-infected cell elimination. Fc gamma RIIIA/CD16a regulates NK cell survival, proliferation, and prevents progenitor apoptosis. It forms signaling complexes, driving intracellular cascades for NK cell activation. The protein plays a crucial role in antitumor activities, triggering TNFA-dependent ADCC. In Dengue virus infection, it contributes to pathogenesis via antibody-dependent enhancement (ADE). Fc gamma RIIIA/CD16a Protein, Human (F176V, CHO, His) is the recombinant human-derived Fc gamma RIIIA/CD16a protein, expressed by CHO , with C-His labeled tag and F176V mutation. The total length of Fc gamma RIIIA/CD16a Protein, Human (F176V, CHO, His) is 192 a.a., with molecular weight of 40-45 kDa.

HY-P75645

	Fc gamma RIIA/CD32a Protein, Human (H167R, HEK293, His-Avi) low affinity Immunoglobulin Gamma Fc Region Receptor II-a; CD32; FCGR2A; FCG2; IGFR2	Human	HEK293
	Fc gamma RIIA/CD32a Protein plays a pivotal role, specifically binding to the Fc region of immunoglobulins gamma as a low-affinity receptor. Interacting with IgG, it initiates cellular responses against pathogens, crucial for immune modulation. Notably, the protein promotes opsonized antigen phagocytosis, contributing to immune defense. Engaging with IGHG1, INPP5D/SHIP1, INPPL1/SHIP2, APCS, FGR, and HCK, it participates in intricate signaling pathways, highlighting its multifaceted role in orchestrating diverse immune responses. Fc gamma RIIA/CD32a Protein, Human (H167R, HEK293, His-Avi) is the recombinant human-derived Fc gamma RIIA/CD32a protein, expressed by HEK293 , with C-Avi, C-His labeled tag and H167R mutation. The total length of Fc gamma RIIA/CD32a Protein, Human (H167R, HEK293, His-Avi) is 183 a.a., with molecular weight of ~34-40 kDa.

HY-P78879

	Fc gamma RIIIA/CD16a Protein, Cynomolgus (Biotinylated, HEK293, His-Avi) low affinity immunoglobulin gamma Fc region receptor III-A; FcRIIIa; FcR-10; CD16a; FCGR3A; IGFR3	Cynomolgus	HEK293
	FcγRIIIA/CD16a Protein, a receptor for IgG, optimally activates upon clustered antigen-IgG complex binding, inducing antibody-dependent cellular cytotoxicity (ADCC). It mediates IgG effector functions on natural killer cells, limiting viral load. FcγRIIIA generates memory-like adaptive NK cells, crucial for NK cell activation. As a Fc-binding subunit, it forms signaling complexes with CD247 and/or FCER1G, initiating intracellular pathways. FcγRIIIA costimulates NK cells, triggering lysis independently of IgG binding. It plays a role in antitumor activities, induces TNFA-dependent ADCC, interacts with CD2 for NK cell activation, and interacts with S100A4, inhibiting FCGR3A phosphorylation. Fc gamma RIIIA/CD16a Protein, Cynomolgus (Biotinylated, HEK293, His-Avi) is the recombinant cynomolgus-derived Fc gamma RIIIA/CD16a protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of Fc gamma RIIIA/CD16a Protein, Cynomolgus (Biotinylated, HEK293, His-Avi) is 192 a.a., with molecular weight of 36-45 kDa.

HY-P75209

	Fc gamma RIIIA/CD16a Protein, Human (F176V, HEK293, His) low affinity immunoglobulin gamma Fc region receptor III-A; FcRIIIa; FcR-10; CD16a; FCGR3A; IGFR3	Human	HEK293
	Fc gamma RIIIA/CD16a protein is a receptor for the Fc fragment of IgG and activates antibody-dependent cellular cytotoxicity (ADCC) upon binding to antigen-IgG complexes. It mediates IgG effector functions on NK cells, generating memory-like adaptive NK cells to efficiently eliminate virally infected cells. Fc gamma RIIIA/CD16a Protein, Human (F176V, HEK293, His) is the recombinant human-derived Fc gamma RIIIA/CD16a protein, expressed by HEK293 , with C-His labeled tag and F176V, , , , mutation. The total length of Fc gamma RIIIA/CD16a Protein, Human (F176V, HEK293, His) is 192 a.a., with molecular weight of ~44.2 kDa.

HY-P72885

	Fc gamma RIIIA/CD16a Protein, Human (F176V, HEK293, His-Avi) low affinity immunoglobulin gamma Fc region receptor III-A; FcRIIIa; FcR-10; CD16a; FCGR3A; IGFR3	Human	HEK293
	Fc gamma RIIIA/CD16a Protein, a receptor for the Fc fragment of IgG, activates antibody-dependent cellular cytotoxicity (ADCC) upon binding antigen-IgG complexes. It mediates IgG effector functions on NK cells, generating memory-like adaptive NK cells for efficient virus-infected cell elimination. Fc gamma RIIIA/CD16a regulates NK cell survival, proliferation, and prevents progenitor apoptosis. It forms signaling complexes, driving intracellular cascades for NK cell activation. The protein plays a crucial role in antitumor activities, triggering TNFA-dependent ADCC. In Dengue virus infection, it contributes to pathogenesis via antibody-dependent enhancement (ADE). Fc gamma RIIIA/CD16a Protein, Human (F176V, HEK293, His-Avi) is the recombinant human-derived Fc gamma RIIIA/CD16a protein, expressed by HEK293 , with C-Avi, C-His labeled tag and F176V mutation. The total length of Fc gamma RIIIA/CD16a Protein, Human (F176V, HEK293, His-Avi) is 192 a.a., with molecular weight of ~46 kDa.

HY-P77553

	Fc gamma RIIIA/CD16a Protein, Human (Biotinylated, F176V, HEK293, His-Avi) low affinity immunoglobulin gamma Fc region receptor III-A; FcRIIIa; FcR-10; CD16a; FCGR3A; IGFR3	Human	HEK293
	Fc gamma RIIIA/CD16a Protein, a receptor for the Fc fragment of IgG, activates antibody-dependent cellular cytotoxicity (ADCC) upon binding antigen-IgG complexes. It mediates IgG effector functions on NK cells, generating memory-like adaptive NK cells for efficient virus-infected cell elimination. Fc gamma RIIIA/CD16a regulates NK cell survival, proliferation, and prevents progenitor apoptosis. It forms signaling complexes, driving intracellular cascades for NK cell activation. The protein plays a crucial role in antitumor activities, triggering TNFA-dependent ADCC. In Dengue virus infection, it contributes to pathogenesis via antibody-dependent enhancement (ADE). Fc gamma RIIIA/CD16a Protein, Human (Biotinylated, F176V, HEK293, His-Avi) is the recombinant human-derived Fc gamma RIIIA/CD16a protein, expressed by HEK293 , with C-Avi, C-His labeled tag and F176V mutation. The total length of Fc gamma RIIIA/CD16a Protein, Human (Biotinylated, F176V, HEK293, His-Avi) is 192 a.a., with molecular weight of ~48 kDa.

HY-P7848

	Fc gamma RIIIB/CD16b Protein, Human (NA2, HEK293, His) rHulow affinity immunoglobulin gamma Fc region receptor III-B/CD16b, His; low affinity immunoglobulin gamma Fc region receptor III-B; Fc-gamma RIII-beta; FcR-10; IgG Fc receptor III-1; FCG3; FCGR3; CD16b and FCGR3B	Human	HEK293
	Fc gamma RIIIB/CD16b Protein, a low-affinity receptor for IgG, binds complexed or monomeric IgG. Unlike Fc gamma RIIIA, it cannot mediate antibody-dependent cytotoxicity or phagocytosis. Instead, Fc gamma RIIIB may act as a trap for immune complexes, circulating without activating neutrophils. Existing as a monomer, it interacts with INPP5D/SHIP1, implying its role in intracellular signaling pathways linked to immune responses. Fc gamma RIIIB/CD16b Protein, Human (NA2, HEK293, His) is the recombinant human-derived Fc gamma RIIIB/CD16b protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Fc gamma RIIIB/CD16b Protein, Human (NA2, HEK293, His) is 192 a.a., with molecular weight of 35-65 kDa.

HY-P76235

	Fc gamma RIIB/CD32b Protein, Rat (HEK293, His) low affinity Immunoglobulin Gamma Fc Region Receptor II-b; IgG Fc Receptor II-b; CDw32; FcRII-b; CD32; FCGR2B; FCG2; IGFR2	Rat	HEK293
	Fc gamma RIIB/CD32b Protein plays a crucial role, specifically binding to the Fc region of immunoglobulins gamma as a low-affinity receptor. Binding to IgG, it initiates cellular responses against pathogens, highlighting its immune system modulation. Interactions with FGR and LYN underscore its role in signaling pathways, emphasizing its significance in mediating cellular responses and contributing to immune defense against diverse antigens. Fc gamma RIIB/CD32b Protein, Rat (HEK293, His) is the recombinant rat-derived Fc gamma RIIB/CD32b protein, expressed by HEK293, with C-His labeled tag. The total length of Fc gamma RIIB/CD32b Protein, Rat (HEK293, His) is 181 a.a., with molecular weight of 30-50 KDa.

HY-P76207

	Fc gamma RIII/CD16 Protein, Mouse (Biotinylated, HEK293, His-Avi) low affinity immunoglobulin gamma Fc region receptor III; Fcgr3; Fc gamma Receptor III; CD-antigen 16; CD16; FcRIII; IgG Fc receptor III	Mouse	HEK293
	Fc gamma RIII/CD16 Protein, a low-affinity receptor for IgG1, IgG2a, and IgG2b, is crucial for mediating neutrophil activation in response to IgG complexes. It functions redundantly with Fcgr4 and interacts with INPP5D/SHIP1, emphasizing its involvement in intracellular signaling pathways linked to immune responses. Fc gamma RIII/CD16's significance lies in facilitating cellular activation triggered by immunoglobulin binding. Fc gamma RIII/CD16 Protein, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived Fc gamma RIII/CD16 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Fc gamma RIII/CD16 Protein, Mouse (Biotinylated, HEK293, His-Avi) is 215 a.a., with molecular weight of ~24.4 KDa.

HY-P70708

	Fc gamma RIII/CD16 Protein, Mouse (185a.a, HEK293, His) low affinity immunoglobulin gamma Fc region receptor III; Fcgr3; Fc gamma Receptor III; CD-antigen 16; CD16; FcRIII; IgG Fc receptor III	Mouse	HEK293
	Fc gamma RIII/CD16 Protein, a low-affinity receptor for IgG1, IgG2a, and IgG2b, is crucial for mediating neutrophil activation in response to IgG complexes. It functions redundantly with Fcgr4 and interacts with INPP5D/SHIP1, emphasizing its involvement in intracellular signaling pathways linked to immune responses. Fc gamma RIII/CD16's significance lies in facilitating cellular activation triggered by immunoglobulin binding. Fc gamma RIII/CD16 Protein, Mouse (185a.a, HEK293, His) is the recombinant mouse-derived Fc gamma RIII/CD16 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Fc gamma RIII/CD16 Protein, Mouse (185a.a, HEK293, His) is 185 a.a., with molecular weight of 35-40 kDa.

HY-P75211

	Fc gamma RIIB/CD32b Protein, Human (Biotinylated, HEK293, His-Avi) low affinity Immunoglobulin Gamma Fc Region Receptor II-b; IgG Fc Receptor II-b; CDw32; FcRII-b; CD32; FCGR2B; FCG2; IGFR2	Human	HEK293
	Fc gamma RIIB/CD32b protein is a low-affinity receptor for immunoglobulin gamma and plays a key role in immune responses. It mediates phagocytosis of immune complexes and regulates antibody production by B cells. Fc gamma RIIB/CD32b Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived Fc gamma RIIB/CD32b protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Fc gamma RIIB/CD32b Protein, Human (Biotinylated, HEK293, His-Avi) is 179 a.a., with molecular weight of 30-35 kDa.

HY-P75649

	Fc gamma RIIB/CD32b Protein, Mouse (Biotinylated, HEK293, His-Avi) low affinity Immunoglobulin Gamma Fc Region Receptor II-b; IgG Fc Receptor II-b; CDw32; FcRII-b; CD32; FCGR2B; FCG2; IGFR2	Mouse	HEK293
	Fc gamma RIIB/CD32b protein is essential for IgG binding activity and participates in immune responses and various processes. It plays a role in antigen processing and presentation, negative regulation of immune processes, and phagocytosis. Fc gamma RIIB/CD32b Protein, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived Fc gamma RIIB/CD32b protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Fc gamma RIIB/CD32b Protein, Mouse (Biotinylated, HEK293, His-Avi) is 217 a.a., with molecular weight of 38-43 kDa.

HY-P76206

	Fc gamma RIII/CD16 Protein, Mouse (215a.a, HEK293, His) low affinity immunoglobulin gamma Fc region receptor III; Fcgr3; Fc gamma Receptor III; CD-antigen 16; CD16; FcRIII; IgG Fc receptor III	Mouse	HEK293
	Fc gamma RIII/CD16 Protein, a low-affinity receptor for IgG1, IgG2a, and IgG2b, is crucial for mediating neutrophil activation in response to IgG complexes. It functions redundantly with Fcgr4 and interacts with INPP5D/SHIP1, emphasizing its involvement in intracellular signaling pathways linked to immune responses. Fc gamma RIII/CD16's significance lies in facilitating cellular activation triggered by immunoglobulin binding. Fc gamma RIII/CD16 Protein, Mouse (215a.a, HEK293, His) is the recombinant mouse-derived Fc gamma RIII/CD16 protein, expressed by HEK293 , with C-His labeled tag. The total length of Fc gamma RIII/CD16 Protein, Mouse (215a.a, HEK293, His) is 215 a.a., with molecular weight of 35-44 KDa.

HY-P70491

	Fc gamma RIIB/CD32b Protein, Human (HEK293, His) low affinity Immunoglobulin Gamma Fc Region Receptor II-b; IgG Fc Receptor II-b; CDw32; Fc-Gamma RII-b; Fc-Gamma-RIIb; FcRII-b; CD32; FCGR2B; FCG2; IGFR2	Human	HEK293
	Fc gamma RIIB/CD32b protein is a low-affinity receptor for immunoglobulin gamma and plays a key role in immune responses. It mediates phagocytosis of immune complexes and regulates antibody production by B cells. Fc gamma RIIB/CD32b Protein, Human (HEK293, His) is the recombinant human-derived Fc gamma RIIB/CD32b protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Fc gamma RIIB/CD32b Protein, Human (HEK293, His) is 175 a.a., with molecular weight of 22-30 kDa.

HY-P76799

	Fc gamma RIIB/CD32b Protein, Cynomolgus (Biotinylated, HEK293, His-Avi) low affinity Immunoglobulin Gamma Fc Region Receptor II-b; IgG Fc Receptor II-b; CDw32; Fc-Gamma RII-b; Fc-Gamma-RIIb; FcRII-b; CD32; FCGR2B; FCG2; IGFR2	Cynomolgus	HEK293

HY-P70711

	Fc gamma RIIA/CD32a Protein, Human (HEK293, His) low affinity immunoglobulin gamma Fc region receptor II-a; IgG Fc receptor II-a; CDw32; Fc-gamma RII-a; Fc-gamma-RIIa; FcRII-a; CD32; FCGR2A; FCG2; FCGR2A1; IGFR2	Human	HEK293
	Fc gamma RIIA/CD32a Protein plays a pivotal role, specifically binding to the Fc region of immunoglobulins gamma as a low-affinity receptor. Interacting with IgG, it initiates cellular responses against pathogens, crucial for immune modulation. Notably, the protein promotes opsonized antigen phagocytosis, contributing to immune defense. Engaging with IGHG1, INPP5D/SHIP1, INPPL1/SHIP2, APCS, FGR, and HCK, it participates in intricate signaling pathways, highlighting its multifaceted role in orchestrating diverse immune responses. Fc gamma RIIA/CD32a Protein, Human (HEK293, His) is the recombinant human-derived Fc gamma RIIA/CD32a protein, expressed by HEK293 , with C-6*His labeled tag and H167 mutation. The total length of Fc gamma RIIA/CD32a Protein, Human (HEK293, His) is 183 a.a., with molecular weight of 25-34 kDa.

HY-P76800

	Fc gamma RIIB/CD32b Protein, Cynomolgus (217a.a, HEK293, His) low affinity Immunoglobulin Gamma Fc Region Receptor II-b; IgG Fc Receptor II-b; CDw32; Fc-Gamma RII-b; Fc-Gamma-RIIb; FcRII-b; CD32; FCGR2B; FCG2; IGFR2	Cynomolgus	HEK293

HY-P70478

	Fc gamma RIIA/CD32a Protein, Human (183a.a, H167R, HEK293, His) low affinity Immunoglobulin Gamma Fc Region Receptor II-a; IgG Fc receptor II-a; CDw32; Fc-Gamma RII-a; Fc-Gamma-RIIa; FcRII-a; CD32; FCGR2A; CD32; FCG2; FCGR2A1; IGFR2	Human	HEK293
	Fc gamma The RIIA/CD32a protein plays a key role as a low-affinity receptor that specifically binds to the Fc region of immunoglobulin gamma. It interacts with IgG to initiate cellular responses against pathogens, which is critical for immune regulation. Fc gamma RIIA/CD32a Protein, Human (183a.a, H167R, HEK293, His) is the recombinant human-derived Fc gamma RIIA/CD32a protein, expressed by HEK293 , with C-6*His labeled tag and H167R, , , , mutation. The total length of Fc gamma RIIA/CD32a Protein, Human (183a.a, H167R, HEK293, His) is 183 a.a., with molecular weight of 27-32 kDa.

HY-P70705

	Fc gamma RIIIA/CD16a Protein, Human (HEK293, His) 1 Publications Verification low affinity Immunoglobulin Gamma Fc Region Receptor III-A; CD16a Antigen; Fc-Gamma RIII-Alpha; Fc-Gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc Receptor III-2; CD16a; FCGR3A; CD16A; FCG3; FCGR3; IGFR3	Human	HEK293
	Fc gamma RIIIA/CD16a protein is a receptor for the Fc fragment of IgG and activates antibody-dependent cellular cytotoxicity (ADCC) upon binding to antigen-IgG complexes. It mediates IgG effector functions on NK cells, generating memory-like adaptive NK cells to efficiently eliminate virally infected cells. Fc gamma RIIIA/CD16a Protein, Human (HEK293, His) is the recombinant human-derived Fc gamma RIIIA/CD16a protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Fc gamma RIIIA/CD16a Protein, Human (HEK293, His) is 192 a.a., with molecular weight of 36-44 kDa.

HY-P7806

	Fc gamma RIIIA/CD16a Protein, Cynomolgus (HEK293, His) rCynFc-gamma receptor 3A/CD16a, His; low affinity Immunoglobulin Gamma Fc Region Receptor III-A; CD16a Antigen; Fc-Gamma RIII-Alpha; Fc-Gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc Receptor III-2; CD16a; FCGR3A; CD16A; FCG3; FCGR3; IGFR3	Cynomolgus	HEK293
	FCGR3A is a receptor for the Fc portion of immunoglobulin G that enhances antibody-dependent cell-mediated cytotoxicity and antibody-dependent viral infection. FCGR3A is also a potential immune oncogenic molecule and is related to the level of tumor immune infiltration. FCGR3A is often used as a biomarker with prognostic value in prostate cancer (PCa). Fc gamma RIIIA/CD16a Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived Fc gamma RIIIA/CD16a protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Fc gamma RIIIA/CD16a Protein, Cynomolgus (HEK293, His) is 186 a.a., with molecular weight of 30-40 kDa.

Cat. No.	Product Name	Chemical Structure

HY-W001909S

Myosmine-d4
Myosmine-d₄ is the deuterium labeled Myosmine. Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM[1][2].

HY-103414S

Raclopride-d5 hydrochloride
Raclopride-d₅ (hydrochloride) is the deuterium labeled Raclopride. Raclopride is a dopamine D2/D3 receptor antagonist, which binds to D2 and D3 receptors with dissociation constants (Kis) of 1.8 nM and 3.5 nM, respectively, but has a very low affinity for D1 and D4 receptors with Kis of 18000 nM and 2400 nM, respectively[1][2].

HY-B0251S

Eplerenone-d3
Eplerenone-d₃ is the deuterium labeled Eplerenone. Eplerenone (Epoxymexrenone) is a selective, competitive and oreally active aldosterone antagonist with an IC50 of 138 nM. Eplerenone has low affinity for progesterone, androgen, estrogen and glucocorticoid receptors. Eplerenone can be used for hypertension and heart failure after myocardial infarction reserch[1][2].

HY-119696S

MTIC-d3
MTIC-d₃ is deuterium labeled MTIC. MTIC is the active metabolite of Temozolomide (TMZ). MITC has lower bioavailability in the brain compared with TMZ, because the agent’s permeability through biological barriers and tumor cell membranes affects bioavailability. MITC exhibits low affinity to biological membrane[1].

HY-15234S

Fluticasone furoate-d3
Fluticasone furoate-d₃ is deuterium labeled Fluticasone furoate. Fluticasone furoate is a topical, intranasal, enhanced-affinity synthetic trifluorinated corticosteroid with a Kd of 0.3 nM. Fluticasone furoate has potent anti-inflamatory and anti-asthmatic activity, and low systemic exposure. Fluticasone furoate has the potential for allergic rhinitis treatment[1][2].

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